Reese Witherspoon and her daughter Ava Elizabeth Phillippe look as if they are about to embark on a girls vacation, as they head off on a private jet leaving from Van Nuys airport in California.

Reese’s sons Deacon Phillippe and Tennessee Toth are nowhere to be seen and husband Jim Toth is also absent.

Yesterday Reese was seen leaving a skincare spa in Beverly Hills, before heading to a “Stand Up 2 Cancer” telethon event. Reese and her husband Jim Toth were executive producers of the event which raises money for cancer research. Hosted by “Black-ish” star Anthony Anderson, “Modern Family” actress Sofia Vergara and husband-and-wife Ken Jeong and Tran Ho, the telethon boasted a host of singing, movie and tv stars and was streamed commercial free on ABC, CBS, Fox and NBC.

With that work done, Ava and Reese are jetting away.